Chapter 81 Tuberculosis Q&A (1 of 6) Sample Questions

1. A 30-year-old pregnant woman in her first trimester has a latent tuberculosis (TB) infection (LTBI). She is living in an INH-resistant area. The best choice her doctor can give her is:
  1. A. Wait until the second trimester to initiate treatment
  2. B. Start immediate INH + Rifadin
  3. C. Rifadin for 4 months
  4. D. INH+RIF+PZA+EM for 6 months
Answer
Ans: C
Tips: This is not an active therapy, therefore no aggressive therapy required; the need for combinations is not needed. Patient is in INH-resistant area thus better option is Rifadin for 4 months. However, in patients without high risk of disease, withhold latent therapy until 3 months postpartum to reduce the risk of hepatotoxicity.