Chapter 80 Community Acquired Pneumonia Q&A (1 of 23) Sample Questions

1. Florence is a 72-year-old patient with COPD who is admitted to the hospital due to acute pneumonia. She is allergic to penicillin. She is on the following medications: Aminophylline infusion by IV drip at a rate of 40mg/h, Ceftazidime 1g IVPB q8h, Gentamicin 100 mg IVPB q12h and Albuterol 5% nebulizer solution q4h prn. The culture and sensitivity report for the sputum specimen indicates the following minimum inhibitory concentration (MICs):
Ceftazidime ≤ 8 ug/ml
Mezlocillin ≤ 8 ug/ml
Gentamicin = 4 ug/ml
Tobramycin ≤ 0.5 ug/ml
Ciprofloxacin = 8 ug/ml
Based on these results, a rational therapeutic decision would be to:
  1. A. Continue existing regimens without change.
  2. B. Continue Ceftazidime only.
  3. C. Continue Gentamicin; change Ceftazidime to Mezlocillin.
  4. D. Change Gentamicin to Tobramycin; continue Ceftazidime.
Answer
Ans: D