Chapter 17 Epilepsy Q&A (1 of 17) Sample Questions

1. A 25-year-old woman has been diagnosed with simple partial seizure. Overall, she is healthy and has no comorbidities. Currently, she is using estrogen/progestin combined oral contraceptive. What is the drug of choice to treat simple partial seizure?
  1. A. Lamotrigine
  2. B. Carbamazepine
  3. C. Phenytoin
  4. D. Valproic acid
Answer
Ans: A
Tips: first line therapy for partial seizures are CBZ, lamotrigine, levetiracetam, phenytoin. Lexi-interact: Lamotrigine + OCPs = category C (monitoring required)
CBZ + OCP = Category D (modify the therapy). Valproic acid + OCP = A, safe to use.