Chapter 133 Dosage Forms Q&A (1 of 9) Sample Questions

1. Lansoprazole for a child with Gastroesophageal reflux disease (GERD) is insoluble in water and sparingly soluble in alcohol. In what formulation should it be prepared?
  1. A. Elixir
  2. B. Suspension
  3. C. Syrup
  4. D. Solution
Ans: B
Tips: Avoid alcohol containing product to treat GERD, it can precipitate GERD. Suspension contains insoluble solid particle in water or alcohol, soluble in alkali, decomposed by hot water.
Elixir is clear solution with alcohol. Elixir is a clear solution with alcohol. An elixir must be the lowest alcoholic quantity that will dissolve completely the active ingredient(s) and give a clear solution. It is generally chosen if it is sparingly sol. Otherwise it medication should be formulation into a suspension.