Chapter 13 Psychosis Q&A (1 of 51) Sample Questions

1. MKT is a 40 year old woman who was diagnosed with hallucinations and delusional thoughts. She lives with her husband and two children. She is paranoid and has serious concerns losing her family because she thinks she is obese and not attractive. She is on metformin 500 mg tid. She has no known allergies. Her physician considers prescribing olanzapine but would like the input of pharmacist first. What recommendation should provide MKT prescriber?
  1. A. Paliperidone
  2. B. Aripiprazole
  3. C. Ziprasidone
  4. D. Lurasidone
Answer
Ans: C
Tips: Among SGAs, clozapine and olanzapine are associated with the greatest weight gain followed by quetiapine, risperidone, paliperidone and aripiprazole. Asenapine, lurasidone and ziprasidone are associated with minimal or no weight gain. Ziprasidone is only drug has bot improvement in weight and metabolic parameters. Clozapine and olanzapine have the highest risk. Aripiprazole, asenapine, lurasidone, paliperidone, risperidone and ziprasidone have minimal risk of glucose abnormalities.